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Publications

Tunçkanat T, Gendron A, Sadler Z, Neitz A, Byquist S, Lie TJ, Allen KD. Lysine 2,3-Aminomutase and a Newly Discovered Glutamate 2,3-Aminomutase Produce β-Amino Acids Involved in Salt Tolerance in Methanogenic Archaea. Biochemistry. 2022; 61(11): 1077-1090

https://doi.org/10.1021/acs.biochem.2c00014

 

Lie TJ, Kuo YP, Leite M, Costa KC, Harwood CS, Leigh JA. A Genetic Study of Nif-Associated Genes in a Hyperthermophilic Methanogen. Microbiol Spectr. 2022 Feb 23;10(1):e0209321.

https://doi.org/10.1128/spectrum.02093-21

 

Ma HY, Yang HH, Zheng XJ, Lie TJ, Yan W. Promoting photo-fermentative hydrogen production performance by substituting the rnf promoter in Rhodobacter capsulatus. Int. Journal of Hydrogen Energy. 2021; 46(5):3742-3752

https://doi.org/10.1016/j.ijhydene.2020.10.270

 

Richards MA, Lie TJ, Zhang J, Ragsdale SW, Leigh JA, Price ND. Exploring Hydrogenotrophic Methanogenesis: a Genome Scale Metabolic Reconstruction of Methanococcus maripaludis. J Bacteriol. 2016;198(24):3379-3390. 

https://doi.org/10.1128/jb.00571-16

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Yoon SH, Turkarslan S, Reiss DJ, Pan M, Burn JA, Costa KC, Lie TJ, Slagel J, Moritz RL, Hackett M, Leigh JA, Baliga NS. A systems level predictive model for global gene regulation of methanogenesis in a hydrogenotrophic methanogen. Genome Res. 2013 Nov;23(11):1839-51

https://doi.org/10.1101/gr.153916.112     

 

Lie TJ, Costa KC, Pak D, Sakesan V, Leigh JA. Phenotypic evidence that the function of the [Fe]-hydrogenase Hmd in Methanococcus maripaludis requires seven hcg (hmd co-occurring genes) but not hmdII. FEMS Microbiol Lett. 2013 Jun;343(2):156-60.

https://doi.org/10.1111/1574-6968.12141

 

Costa KC, Lie TJ, Xia Q, Leigh JA. VhuD facilitates electron flow from H2 or formate to heterodisulfide reductase in Methanococcus maripaludis. J Bacteriol. 2013 Nov;195(22):5160-5

https://doi.org/10.1128/jb.00895-13

 

Costa KC, Lie TJ, Jacobs MA, Leigh JA. H2 -independent growth of the hydrogenotrophic methanogen Methanococcus maripaludis. mBio. 2013;4(2):e00062-13.

https://doi.org/10.1128/mbio.00062-13

 

Lie TJ, Costa KC, Lupa B, Korpole S, Whitman WB, and JA Leigh. 2012. An essential anaplerotic role for the energy-converting hydrogenase Eha in hydrogenotrophic methanogenesis. PNAS. Sep 18;109(38):15473-8.

https://doi.org/10.1073/pnas.1208779109

 

Wisedchaisri G, Dranow DM, Lie TJ, Bonanno JB, Patskovsky Y, Ozyurt SA, Sauder JM, Almo SC, Wasserman SR, Burley SK, Leigh JA and T Gonen. 2010. Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR. Structure. Nov 10; 18(11): 1512-21

https://doi.org/10.1016/j.str.2010.08.014

 

Costa KC, Wong PM, Wang TS, Lie TJ, Dodsworth JA, Swanson I, Burn JA, Hackett M and JA Leigh.  2010. Protein complexing in a methanogen suggests electron bifurcation and electron delivery from formate to heterodisulfide reductase. PNAS Jun 15;107(24):11050-5

https://doi.org/10.1073/pnas.1003653107

 

Lie TJ, Hendrickson EL, Niess UM, Haydock AK, Moore, BC and JA Leigh. 2010. Overlapping repressor binding sites regulate expression of Methanococcus maripaludis glnK1 operon.  Mol Microbiol. Feb;75(3):775-762.

https://doi.org/10.1111/j.1365-2958.2009.07016.x

 

Xia, Q., T. Wang,E. L. Hendrickson, T. J. Lie, M. Hackett, and J. A. Leigh.  2009. Quantitative proteomics of nutrient limitation in the hydrogenotrophic methanogen Methanococcus maripaludis.  BMC Microbiology. Jul; 23 (9): 149

https://doi.org/10.1186/1471-2180-9-149

 

Lie TJ and JA Leigh. 2007. Genetic screen for regulatory mutations in Methanococcus maripaludis and its use in identification of induction-deficient mutants of the euryarchaeal repressor NrpR.  Appl Environ Microbiol. Oct;73(20):6595-600.

https://doi.org/10.1128/AEM.01324-07

 

Lie TJ, Dodsworth JA, Nickels D and JA Leigh. 2007. Diverse homologues of the archaeal repressor NrpR function similarly in nitrogen regulation. FEMS Microbiol Lett. Jun;271(2):281-8. 

https://doi.org/10.1111/j.1574-6968.2007.00726.x

 

Stolyar, S, Van Dien S, Hillesland KL, Pinel N, Lie TJ, Leigh JA and DA Stahl.  2007. Metabolic modeling of a mutualistic microbial community. Mol Syst Biol. 3:92

https://doi.org/10.1038/msb4100131

 

Lie TJ, Wood GE and JA Leigh. 2005. Regulation of nif expression in Methanococcus maripaludis: roles of the euryarchaeal repressor NrpR, 2-oxoglutarate, and two operators.  J Biol Chem. Feb 18;280(7):5236-41

https://doi.org/10.1074/jbc.M411778200

 

Hendrickson EL et al. (16th of 32 authors) Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis. 2004. J Bacteriol. Oct;186(20):6956-69

https://doi.org/10.1128/jb.186.20.6956-6969.2004

 

Lie TJ and JA Leigh. A novel repressor of nif and glnA expression in the methanogenic archaeon Methanococcus maripaludis. 2003. Mol Microbiol. Jan;47(1):235-46.

https://doi.org/10.1046/j.1365-2958.2003.03293.x

 

Lie TJ and JA Leigh. 2002. Regulatory response of Methanococcus maripaludis to alanine, an intermediate nitrogen source. J Bacteriol. Oct;184(19):5301-6.

https://doi.org/10.1128/jb.184.19.5301-5306.2002

 

Lie TJ, Godchaux W and ER Leadbetter. 1999. Sulfonates as Terminal Electron Acceptors for Growth of Sulfite-Reducing Bacteria (Desulfitobacterium spp.) and Sulfate-Reducing Bacteria: Effects of Inhibitors of Sulfidogenesis. Appl. Environ. Microbiol 65: 4611-4617

https://doi.org/10.1128/AEM.65.10.4611-4617.1999

 

Lie TJ, Clawson ML, Godchaux W and ER Leadbetter. 1999. Sulfidogenesis from 2-aminoethanesulfonate (taurine) fermentation by a morphologically unusual sulfate-reducing bacterium, Desulforhopalus singaporensis sp. nov. Appl. Environ. Microbiol 65: 3328-3334

https://doi.org/10.1128/AEM.65.8.3328-3334.1999

 

Lie TJ, Leadbetter JR and ER Leadbetter. 1998. Metabolism of organosulfur compounds and sulfonates by sulfate-reducing bacteria. Geomicrobiol. J.15: 135-149

https://doi.org/10.1080/01490459809378070

 

Lie TJ, Pitta T, Leadbetter ER, Godchaux W, and JR Leadbetter. 1996. Sulfonates: novel participants in anaerobic respiration. Arch. Microbiol. 166: 204-210

https://doi.org/10.1007/s002030050376

Novel NrpR
Homologs
sulfonates novel
Desulforhopalus singaporensis
Predictive metabolic model
A genetic approach 5 mutants
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